Tirzepatide
Clinical evidence — Human trial data existsWhat it is
A dual GIP/GLP-1 receptor agonist. Licensed as a prescription medicine for diabetes and weight management in some countries; research-grade supply is not that regulated product.
Tirzepatide activates both the GIP and GLP-1 receptors, a dual-incretin mechanism associated with strong appetite and glucose effects in trials. Like semaglutide it is titrated slowly in clinical use.
Research context
Studied in relation to:
- Appetite reduction
- Weight management
- Glucose control
Points in its favour in the literature:
- Strong Phase 3 human data for the licensed drug
- Dual-incretin mechanism
- Robust reported weight outcomes under supervision
Caveats and unknowns:
- Not the monitored pharmacy product
- GI side effects common
- Needs clinical titration
- Dose errors carry real risk
Handling & reference data
Route in published researchSubcutaneous injection is the route most commonly described in the research literature. Once-weekly in clinical use.
Reported half-life~5 days (once-weekly dosing)
Published clinical / research context (not instructions)Licensed use starts 2.5 mg once weekly, titrated up toward 5–15 mg weekly.
Storage (lyophilised)Lyophilised (freeze-dried) powder: refrigerate at 2–8 °C short-term, or freeze at −20 °C or below for long-term storage. Keep sealed and out of light.
Reconstituted solutionOnce reconstituted: keep refrigerated (2–8 °C), protect from light, do not freeze. With bacteriostatic water, commonly used within ~4 weeks; with plain sterile water, within ~24–48 h.
Worked reconstitution example (arithmetic only)e.g. 10 mg vial + 2 mL → 5 mg/mL (5000 mcg/mL).
Available research formats
| Strength | SKU |
|---|---|
| 5mg | TR5 |
| 10mg | TR10 |
| 15mg | TR15 |
| 20mg | TR20 |
| 30mg | TR30 |
| 40mg | TR40 |
| 50mg | TR50 |
| 60mg | TR60 |
| 70mg | TR70 |
| 80mg | TR80 |
| 90mg | TR90 |
| 100mg | TR100 |
| 110mg | TR110 |
| 120mg | TR120 |
Current pricing (THB with USD/GBP conversion) is shown live in the catalogue, which also has a transparent U-100 reconstitution calculator.